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The KGPE-D16's ATX socket C32 little brother, what applies to it should apply to this too as the southbridge/northbridge and platform are pretty much the same.

It is useful for a router/firewall or secure applications device as it has an IOMMU and compatible low wattage CPU's such as the 35W Opteron EE series.

It could also be used as a gaming platform with the Opteron C32 4386 CPU (microcode update required) which is equivalent to an AM3+ FX-8370E